الوصف

The site of anti parasite action of both componets is the good food vacuole of the malaria parasite, where theyare thought to interfere with the conversion of haem, a toxic intermediate produced during haemoglobin breakdown, to the non-toxic haemozoin malaria the interaction between its peroxide bridge and haem iron .Both artemether and lumefantrine have a secondary action involving inhibition of nucleic acid-and protein synthesis within the malaria parasite.